Hmm, that looks like good value .
If I click on the " AmpliTube 4 for Mac/PC" link on the iRig Pro I/O page it takes me to the AmpliTube 4 product page. And, yes, they are the same list price.
And, with iRig Pro I/O, you get AmpliTube for iOS, AmpliTube 4 for Mac/PC, SampleTank 3 SE, T-RackS Deluxe with Mic Room too. I cannot see why anyone would buy AT4 by itself.
As I understand it, the bundled software becomes available after you Register the hSerial Number supplied with the hardware. If so, then purchasing from the local store shouls be OK.
BUT, for official confirmation, please contact IK Multimedia, here:
https://www.ikmultimedia.com/contact-us/ContactIKForm.phpand, to help others, let us know the general answer.